Carcinoma de células de transição da bexiga com metástase pulmonar em cadela

Abstract

The present work aims to report the activities carried out during the pre-professional internship and describe a clinical case of transitional cell carcinoma of the bladder (TCBC) in a female dog. The activities were carried out at the Veterinary Surgery and Diagnosis Clinic (CCDV), between August 14 and November 14, 2023, from Monday to Friday, between 8:30 am and 6:30 pm, totaling 800 hours of work. The activities were carried out in the medical clinic, dentistry, surgery and clinical laboratory sectors for dogs and cats. 423 consultations were carried out, of which 18 were management of hospitalized animals, 73 clinical cases, 125 complementary exams, 49 deworming, 85 vaccinations of cats and 13 of dogs, 81 surgeries in dogs and 44 in cats. The author also participated in 1 sterilization and anti-rabies vaccination campaign for 24 cats and 1 sterilization and anti-rabies vaccination campaign for 13 dogs. Among the clinical cases monitored, a case of CCTB was described, as it is a malignant neoplasm that rarely occurs in the routine of veterinary clinics, although it is the most common neoplasm of the urinary tract in dogs, elderly and sterilized females, comprising approximately 75-90% of epithelial bladder tumors. On August 30, 2023, he was seen at CCDV, Lda. a female Scottish terrier, spayed, 11 years old, with hematuria, dysuria and a history of tumor recurrence after surgical removal. In the biochemical examination, an increase in serum levels of cholesterol, amylase, alanine aminotransferase, gamma glutamyl transferase, alkaline phosphatase, triglycerides and phosphorus was detected. The blood count showed lymphocytopenia and thrombocytosis. Abdominal ultrasound detected focal thickening of the bladder wall, with irregular and hyperechoic contours in the bladder trigone region. Due to recurrence, the size of the neoplasia, and the failure of treatment, a poor prognosis was considered and, with the owner's consent, the dog was euthanized with 10% propofol and potassium chloride. At necropsy, the bladder showed a thickened wall, multiple whitish nodules of firm consistency, cysts in the spleen and liver, and nodules in the lungs. Histopathological examination determined the diagnosis of CCTB. (TRADUÇÃO NOSSA)