Avaliação do nível de velocidade de hemossedimentação eritrocitária e a sua variabilidade em relação com os parâmetros do eritrograma em pacientes atendidos no laboratório de análises clínicas do Hospital Central de Maputo

Abstract

The erythrocyte sedimentation rate (ESR) is a simple but non-specific test that has been used as an essential inflammatory marker to monitor inflammation and some hematological alterations in the treatment of certain diseases, especially in children. The level of ESR can be affected by red blood cell (RBC) indices, and not taking this into account can complicate the interpretation of ESR and the treatment and follow-up of patients. The aim of this study was to assess the level of ESR and its variability in relation to erythrogram parameters at Maputo Central Hospital from April to June. The study was a prospective cross-sectional study, based on data collection directly from the ESR and CBC systems. 361 patients were involved, with a predominance of females (53%) and patients aged 60 or over. Half of the patients had an ESR above 53mm/h, an average of 61mm/h, had a total number of erythrocytes in the blood (GV), with a hypochromia (CHCM), decreased percentage of erythrocytes in the blood (HTC). Among the 50% of patients, some had severe to moderate anemia (HGB), with normal and large erythrocytes (MCV) and a normal and abnormal variation (RDW-SD and RDW-CV). The results showed a significant negative relationship between ESR and GV (r = -0.387; p = 0), ESR and HGB (r = -0.396; p = 0) and ESR and HCT (r = -0.405; p = 0). The change in ESR was also altered in the clinical conditions of stroke, hypertension and urethritis, CRF, BPN, cataract, anemia, pancytopenia and SK. In conclusion, although the ESR test is not indicated for diagnostic purposes, there are several limitations. This study showed an association between ESR and erythrogram parameters. It is necessary for healthcare professionals and the treatment team to pay attention to erythrogram parameters (GV, HGB and HTC) when interpreting and following up VHS results in order to complete the patient treatment process.