Carcinoma de células escamosas na mama de cadela e no pavilhão auricular externo de roedor: aspectos clínicos, patológicos e terapêuticos

Abstract

The skin is the largest organ in the body. It has different types of cells and is exposed to different carcinogens, increasing the risk of developing neoplasms. Between the The most common cutaneous neoplasms include squamous cell carcinoma (SCC), a malignant epithelial neoplasm originating in keratinocytes, occurring in most animals domestic animals, including dogs and rodents, however, the occurrence in the latter is rarely reported. The present work aimed to describe two cases of SCC in the breast of a female dog and in the external ear pinna of a rodent diagnosed at HEV, during the study period (August 2021 to January 2022). Patient 1 (P1) is an entire bitch, of the Boerboel breed, with a nodular formation (10 cm in diameter) in the right caudal abdominal mammary gland (M4), of firm consistency, areas of ulceration, with purulent exudate, foul odor and pain on palpation and, the patient 2 (P2) was a rodent (Cricetomys gambianus), an entire male, with a nodular lesion (0.5 cm long) on ​​the left external ear, of firm consistency, light brown color and irregular surface. Both patients were 7 years old. Complementary exams carried out on P1 revealed in hematology, normocytic normochromic anemia and leukocytosis and, in fine needle aspiration cytology, epithelial cells of different shapes and sizes, the presence of neutrophils and keratin formations. For both patients, the recommended treatment was surgical removal of the neoplastic masses using the techniques: P1 - simple mastectomy and P2 - lumpectomy and partial and total conchectomies, due to the occurrence of two recurrences. The histopathological examination of the surgically removed fragments defined well-differentiated SCC, Grade I, as P1 and P2. The prognosis was defined based on the following aspects: patient age, size of the neoplasm, presence of ulceration and necrosis, involvement of regional lymph nodes, metastases, degree of cellular differentiation and histological type, so for P1 it was reserved and for P2 in the initial evaluation it was favorable and after the first shellectomy it was considered reserved. (TRADUÇAO NOSSA)